Hello, I am completely new to the subject of mushrooms and co.
I've watched a lot of videos and read a lot, but I couldn't find the answer to my question (sorry if it's already written somewhere) 😅.
I have been struggling with depression for years and am currently in a very difficult, almost unbearable state again. Therapy and antidepressants were only ever effective for a short time. Now I have learned that mushrooms can help. I would like to start with microdosing. Official therapies with psilocybin are also offered. But the process is very different from microdosing. A "higher" dose is taken twice where you have visions/hallucinations or whatever. That's supposed to help. But you don't have this effect with microdosing.
Therefore, the question arises as to whether, in addition to microdosing, higher doses should also be used to make faster or more effective progress against depression?
It may also be that the idea is completely wrong 😅.
Thank you for your answers 🩷
Hello and welcome to the forum.
Both methods can be used individually or together.
Many people are afraid of psychedelic experiences and then microdosing is ideal because it has no psychotropic effect. What often happens over time is that people lose their fear of psychedelic dosing through microdosing and become convinced that they need one or more psychedelic experiences to cure their illness.
It is certainly not an "either-or" - it also happens the other way around, that people become convinced after a psychedelic experience that they should start microdosing and if one were looking for "maximum therapeutic effect", high dosing on weekends and microdosing during the week would be feasible.
However, this is difficult to do in addition to "normal life & work" because it involves too much preoccupation with the past and the consequences of one's own experiences and is mentally quite exhausting.
However, it is possible for a limited period of intensive healing, when nothing else is at stake but healing.
So, the idea is correct and it very often happens automatically that after a period of microdosing, people also dose up, many of them cautiously at first.
Important information for all those who have taken psychotropic drugs (especially SSRIs): these toxins destroy brain receptors and even decades later these people need much higher doses!
Typical high doses range from 20-30g of fresh sclerotia or 1.5 to 3.5g of dry magic mushrooms.
People damaged by psychotropic drugs need 5-20 times as much and therefore cannot use sclerotia and often only feel slight effects from magic mushrooms at 10g to 15g, and 50g of dry magic mushrooms is often a medium dose! Extraction becomes a prerequisite in order to be able to have an intense psychedelic experience at all.
Important information for all those who have taken psychotropic drugs (especially SSRIs): these toxins destroy brain receptors
I have only heard of this effect when using (too much ?) mdma, you will have more reliable information about ssri`s than I do, I only had contact with ssri`s for about 6 months - for this period of time it helped to get the mental motor going again (20 mg cytalopram/6 months).
Nevertheless, I wasn't entirely comfortable with it, and it only happened once - and that was about 10 years ago. I had a much better feeling with mushrooms, and I would do it again at any time.
It is important to dry the mushrooms really well, otherwise they quickly start to rot and cause nasty diarrhea if you take them anyway. The proof of the pudding is in the eating ...
I started with mushrooms at 0.1-0.2 grams a day, sometimes twice a day. The mood-lifting effect set in on the same day. I have also increased the dose to 0.5 grams for a short time - without noticeably tripping. Once I took 1 gram - then it slowly started. It was okay - the environment was there at the time, but 1 g would be rather inappropriate for me to cope with everyday life, everything was too euphoric overall - people might look at me funny if I didn't pull myself together.
Most of the people around me who might benefit from mushrooms are afraid of them because they are afraid that traumas and bad experiences from the past might come up again, because they automatically associate mushrooms with tripping, and there are very few people in my environment to whom I would not recommend this out of a dull feeling, because they have struggled with delusions in the past and I don't know whether they wouldn't take far too much at inappropriate times according to the motto "a lot helps a lot" - that would be too confusing for me. 0.1-0.2 grams has turned out to be totally harmless and positive for me. In addition, you can play with the dose at suitable times, the duration of effect is only about 6 hours, and should it happen that it was a little too much, it won't take forever for it to wear off again. However, it is probably better not to drive on the road when experimenting.
I've also tried growing from scratch myself (not with the ready-made kits, but with a mycelium syringe, grain spawn, sterilization, etc.) it's a great feeling to grow your own antidepresiiva, but I did it all too warm and too moist - 2nd attempt to follow ... 🙂
I'm not a doctor myself, so I can only reproduce what google spits out:
Downregulation/desensitization (adaptation): The increased serotonin supply causes the brain to react by reducing the number or sensitivity of certain serotonin receptors (e.g. 5-HT4, 5-HT1A). This is not damage, but an adaptive process that may be related to the therapeutic effect.
There are not only good people working in the pharmaceutical industry who selflessly just want to help other people, but also those who are primarily interested in making a lot of money - and there are more than enough cases where it has been proven that the latter was probably much more important than the former. My trust in this branch of business is not particularly high either.
With mushrooms (psylocobin), however, one often reads about the opposite effect. Long-term intake tends to mean that less has to be taken to achieve the same positive effect. I'm wondering why this might be, as the brain is also offered an increased supply of serotonin, as psylocobin uses the same receptor. Theoretically, it should also make you less sensitive. I haven't microdosed long enough to be able to confirm this from my own experience.
apart from the other things that microdosing entails: e.g. I took 2 puffs of the joint and realized that I don't really need the effect of the thc at all.
